• MD, PhD
    Title
  • Dermatology, Skin Cancer, Venereology
    Specialization
  • English, Greek
    Languages

Short Bio


Dr. Maria Sifaki is a researcher specializing in the biochemical and immunological aspects of growth factors, proteoglycans, and melanoma, with a focus on their impact on biosynthesis and cell behavior.

About the Doctor


Dr. Maria Sifaki holds a Ph.D. in Biochemical and Immunological Studies, with a thesis focused on the action of growth factors on the biosynthesis of secreted chondroitin and dermatan sulfate proteoglycans in melanoma and normal melanocyte cell lines. Throughout their career, they have contributed significantly to understanding the molecular mechanisms of melanoma, particularly in the role of growth factors like fibroblast growth factor in cell migration, adhesion, and proliferation. Dr. Maria Sifaki has been involved in several high-impact publications related to proteoglycans, melanoma cell biology, and growth factor modulation, collaborating with notable researchers in the field.

Accreditations
  • Ph.D. in Biochemical and Immunological Studies.
Training & Experience

Professional positions held:

  • Researcher at various international institutions.
  • Collaborator in several high-impact research projects on melanoma and growth factors.

Academic positions held:

  • –

Training & Studies:

  • Ph.D. in Biochemical and Immunological Studies.
  • Postdoctoral research in melanoma cell biology.
  • Specialized in growth factors and proteoglycans.

Specialization
  • Biochemical and Immunological Studies
  • Melanoma Cell Biology
  • Growth Factor Modulation
  • Proteoglycans in Cancer Research
  • Cell Adhesion and Migration
Research Interests
  • Melanoma
  • Growth Factors and their Role in Cancer
  • Proteoglycans (Chondroitin, Dermatan, Keratan Sulfate)
  • Fibroblast Growth Factor in Cancer
  • Cell Adhesion and Migration
Publications
  • Lumican, a small Leucine-rich Proteoglycan substituted with Keratan Sulfate Chains is expressed and secreted by Human Melanoma Cells and not normal Melanocytes
    M. Sifaki, M. Assouti, D. Nikitovic, K. Krasagakis, N. K. Karamanos, G. N. Tzanakakis.
    IUBMB Life, 2006, 58(10): 606–610
  • Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines. D. Nikitovic, M. Assouti, M. Sifaki, P. Katonis, K. Krasagakis, N.K. Karamanos, G.N. Tzanakakis.
    The International Journal of Biochemistry & Cell Biology 40 (2008) 72–83.
  • Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism. Georgia Chalkiadaki, Dragana Nikitovic, Aikaterini Berdiaki, Maria Sifaki, Kostantinos Krasagakis. Pavlos Katonis, Nikos K. Karamanos, George N. Tzanakakis.
    Int J Biochem Cell Biol (2009) in press.
  • Botulinum toxin type A- treatment of a patient with multiple cutaneous piloleiomyomas Sifaki MK, Krueger-Krasagakis S, Koutsopoulos A, Evangelou GI, Tosca AD.
    Dermatology. 2009; 218(1): 44-7.
  • Ianoşi S, Ianoşi G, Neagoe D, Ionescu O, Zlatian O, Docea AO, Badiu C, Sifaki M, Tsoukalas D, Tsatsakis AM, Spandidos DA, Călina D.
    Mol Med Rep. 2016 Dec;14(6):5501-5506. doi: 10.3892/mmr.2016.5924. Epub 2016 Nov 4.
  • Lupu M, Caruntu A, Caruntu C, Papagheorghe LML, Ilie MA, Voiculescu V, Boda D, Constantin C, Tanase C, Sifaki M, Drakoulis N, Mamoulakis C, Tzanakakis G, Neagu M, Spandidos DA, Izotov BN, Tsatsakis AM.
    Oncol Rep. 2017 Sep;38(3):1327-1340. doi: 10.3892/or.2017.5817. Epub 2017 Jul 13.
  • Yang SH, Tsatsakis AM, Tzanakakis G, Kim HS, Le B, Sifaki M, Spandidos DA, Tsukamoto C, Golokhvast KS, Izotov BN, Chung G.
    Int J Mol Med. 2017 Sep;40(3):631-636. doi: 10.3892/ijmm.2017.3061. Epub 2017 Jul 10.

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Skin Clinic Maria Sifaki

Skin Clinic Maria Sifaki

61 A. Papandreou Ave., Heraklion

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